Synthesis of tetrazole analogues of amino acids using Fmoc chemistry: isolation of amino free tetrazoles and their incorporation into peptides
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چکیده
منابع مشابه
synthesis of amido alkylnaphthols using nano-magnetic particles and surfactants
we used dbsa and nano-magnetic for the synthesis of amido alkylnaphtols.
15 صفحه اولIncorporation of chlorinated analogues of aliphatic amino acids during cell-free protein synthesis.
3-Chloro-Abu and 4-chloro-Nva are biosynthetically incorporated into E. coli peptidyl-Pro cis-trans isomerase B, as substitutes for Val and Leu, respectively. The extent of incorporation is up to ~90%, and substituted protein is catalytically active. By contrast, 4-chloro-Val is not an effective replacement for Ile.
متن کاملSome Relations between Active Transport of Free Amino Acids into Cells and Their Incorporation into Protein.
Increased cell levels of free amino acids have been found to accompany increased protein synthesis in mammalian cells under a number of conditions, including normal growth (2-6), malignancy (7, S), or in response to hormones (see (g-11), for example). The increased protein formation might result in response to the elevated cellular levels of free amino acids produced by increased active transpo...
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گوشت قرمز یکی از مهم ترین فرآورده های دامی در تأمین پروتئین و انرژی می باشد که در حمل ویتامین های محلول در چربی نیز حائز اهمیت می باشد. انسان مانند سایر مهره داران اسید های چرب ضروری (لینولئیک و آلفا لینولنیک) مورد نیاز خود از طریق غذا تأمین می نماید. اسید های چرب ضروی پیش ساز اسید های چرب غیر اشباع با چند پیوند دوگانه هستند. اسید لینولنیک پیش ساز اسیدهای چرب امگا 3 و اسید لینولئیک نیز پیش ساز ...
Incorporation of nonnatural amino acids into proteins.
The genetic code is established by the aminoacylation of transfer RNA, reactions in which each amino acid is linked to its cognate tRNA that, in turn, harbors the nucleotide triplet (anticodon) specific to the amino acid. The accuracy of aminoacylation is essential for building and maintaining the universal tree of life. The ability to manipulate and expand the code holds promise for the develo...
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ژورنال
عنوان ژورنال: Tetrahedron Letters
سال: 2007
ISSN: 0040-4039
DOI: 10.1016/j.tetlet.2007.07.129